Drug details

Derma-Smoothe/FS (fluocinolone acetonide)

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Derma-Smoothe FS (fluocinolone acetonide) is a topical (for the skin) steroid used to treat atopic dermatitis (a form of eczema), and is also used to treat scalp psoriasis. Derma-Smoothe FS is available in generic form.

The drug is often used to treat Psoriasis .

This drug may have the following side effects:
  • cough,
  • sore throat,
  • fever,
  • acne,
  • blisters,
  • pimples,
  • temporary hair loss,
  • skin rash or irritation around your mouth,
  • skin discoloration,
  • stretch marks, 
  • application site reactions (stinging, burning, irritation, dryness, itching, or redness),
  • excessive hair growth,
  • "hair bumps" (folliculitis),
  • skin thinning,
  • crusting of treated skin,
  • runny or stuffy nose, or
  • red spots or the appearance of tiny veins (especially around your nose, cheeks, or chin).
The following drugs are related to Derma-Smoothe/FS, either as a replacement or used together:
  • Aclovate (alclometasone dipropionate cream, ointment)
  • Impeklo (clobetasol propionate lotion)
  • Cutivate Lotion (fluticasone propionate lotion)
  • Elidel (pimecrolimus cream)
  • Hydro 35 (hydrating topical foam)
  • Neosalus Foam (neosalus hydrating topical foam)
  • Opzelura (ruxolitinib cream)
  • Protopic (tacrolimus)