Drug details

DepoDur (morphine sulfate xr liposome injection)

type of Opioid Analgesics

DepoDur (morphine sulfate) extended-release liposome injection is a long-acting narcotic pain reliever (opiate-type) used to treat pain after major surgery. The brand name DepoDur is discontinued, but generic versions may be available.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • vomiting,
  • diarrhea,
  • fever,
  • lightheadedness,
  • chest pain,
  • breathing that stops,
  • agitation,
  • slow heart rate,
  • hallucinations,
  • fast or pounding heartbeats,
  • twitching,
  • fast heart rate,
  • weak or shallow breathing,
  • loss of coordination,
  • blue colored lips,
  • extreme drowsiness,
  • muscle stiffness,
  • slow breathing with long pauses,
  • sighing,
  • dizziness, and
  • hard to wake up,
  • worsening tiredness or weakness
The following drugs are related to DepoDur, either as a replacement or used together:
  • Ionsys (fentanyl iontophoretic transdermal system)
  • Toradol (ketorolac tromethamine)