Drug details

Xgeva (denosumab)

type of Monoclonal Antibodies, Endocrine

Xgeva (denosumab) Injection is a human IgG2 monoclonal antibody used to treat bone problems that may occur with cancer that has spread (metastasized) to the bones.

This drug may have the following side effects:
  • shortness of breath,
  • nausea,
  • headache,
  • lightheadedness,
  • vomiting,
  • itching,
  • pale skin,
  • tiredness,
  • rash,
  • difficulty breathing, 
  • swelling of your face, lips, tongue, or throat, 
  • confusion, 
  • trouble concentrating,
  • overactive reflexes
  • rapid heart rate, 
  • trouble breathing, 
  • new or unusual pain in your thigh, hip, or groin, 
  • lack of energy, 
  • numbness or tingly feeling around your mouth or in your fingers or toes, 
  • muscle tightness or contraction, and 
The following drugs are related to Xgeva, either as a replacement or used together:
  • Xeloda (capecitabine)
  • Jenloga (clonidine tablets)
  • Taxotere (docetaxel for injection)
  • Tarceva (erlotinib)
  • Menest (estrogens)
  • Evenity (romosozumab-aqqg injection)
  • Iressa (gefitinib)
  • Lupron Depot 11.25 mg (leuprolide acetate for depot suspension)
  • Lupron Depot 7.5 mg (leuprolide acetate for depot suspension)
  • Lupron Depot (leuprolide acetate for depot suspension)
  • Lupron Depot 22.5 (leuprolide acetate for depot suspension injection)
  • Lupron (leuprolide acetate injection)
  • Lupron Depot 3.75 mg (leuprolide acetate injection)
  • Lupron Depot Pediatric (leuprolide acetate injection)
  • Nolvadex (tamoxifen citrate)