Drug details

Vyxeos (daunorubicin and cytarabine for injection)

type of Antineoplastics, Antimetabolite, Antineoplastics, Anthracycline

Vyxeos (daunorubicin and cytarabine) liposome for injection, for intravenous use, is a liposomal combination of an anthracycline topoisomerase inhibitor and a nucleoside metabolic inhibitor, indicated for the treatment of adults with newly-diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC).

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • fever,
  • easy bruising,
  • shortness of breath,
  • chills,
  • chest pain,
  • dizziness,
  • dry mouth,
  • swelling,
  • weakness,
  • severe stomach pain,
  • rapid weight gain,
  • sudden numbness or weakness (especially on one side of the body),
  • problems with vision or balance,
  • coughing up blood,
  • vomit that looks like coffee grounds,
  • skin sores,
  • swollen gums,
  • cold or flu symptoms,
  • fainting
  • cough with mucus,
  • unusual bleeding (nose, mouth, vagina, rectum),
  • any bleeding that will not stop,
  • trouble swallowing or talking,
  • sudden severe headache,
  • black or bloody stools,
  • pain, burning, irritation, or skin changes where the injection was given,
  • severe or ongoing diarrhea,
  • wheezing, and
  • sores or white patches in or around your mouth,
  • bad breath,
  • altered sense of taste,
  • fast, slow, or uneven heart rate,
The following drugs are related to Vyxeos, either as a replacement or used together:
  • Anthim (obiltoxaximab intravenous infusion)
  • Beleodaq (belinostat for injection for intravenous use)
  • Bexxar (tositumomab and iodine 1131 tositumomab)
  • Daurismo (glasdegib tablets)
  • Decadron (dexamethasone)
  • Idhifa (enasidenib tablets)
  • Xospata (gilteritinib tablets)
  • Zevalin (ibritumomab tiuxetan)