Drug details

Sprycel (dasatinib)

type of Antineoplastic Tyrosine Kinase Inhibitors, Chemotherapy Modulating Agents

Sprycel (dasatinib) is a kinase inhibitor that blocks proteins that signal certain cancer cells to divide used to treat Philadelphia chromosome-positive acute lymphoblastic leukemia (resistant to prior or failed therapy) and chronic, accelerated, or myeloid or lymphoid blast phase Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance to prior therapy including imatinib.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • vomiting,
  • diarrhea,
  • fever,
  • easy bruising,
  • pale skin,
  • lightheadedness,
  • shortness of breath,
  • cold hands and feet,
  • confusion,
  • chills,
  • tiredness,
  • chest pain,
  • fluttering in your chest,
  • weakness, and
  • swelling,
  • headache,
  • sore throat,
  • skin pain,
  • mouth sores,
  • muscle cramps,
  • rapid weight gain,
  • pounding heartbeats,
  • extreme tiredness,
  • bloody or tarry stools,
  • coughing up blood,
  • vomit that looks like coffee grounds,
  • pain when you breathe,
  • skin sores,
  • unusual bleeding (nose, mouth, vagina, or rectum),
  • purple or red pinpoint spots under your skin,
  • muscle or joint pain,
  • burning in your eyes,
  • red or purple skin rash that spreads and causes blistering and peeling,
  • severe ongoing nausea,
  • severe headaches,
  • blood in your urine,
  • seizures
  • problems with speech,
  • flu-like symptoms,
  • swelling in your feet, lower legs, or midsection,
  • blue-colored lips and skin,
The following drugs are related to Sprycel, either as a replacement or used together:
  • Alecensa (alectinib capsules)
  • Campath (alemtuzumab)
  • Trisenox (arsenic trioxide injection)
  • Elspar (asparaginase)
  • Rylaze (asparaginase erwinia chrysanthemi (recombinant) - rywn) injection)
  • Symbenda (bendamustine hydrochloride)
  • Bendeka (bendamustine hydrochloride injection)
  • Bosulif (bosutinib tablets)
  • Leustatin (cladribine injection for intravenous infusion only)
  • Copiktra (duvelisi capsules)
  • Cytoxan (cyclophosphamide)
  • Inqovi (decitabine and cedazuridine tablets)
  • Nivestym (filgrastim-aafi injection)
  • Fludara (fludarabine)
  • Mylotarg (gemtuzumab ozogamicin for injection)
  • Gleevec (imatinib mesylate)
  • Tibsovo (ivosidenib tablets)
  • Jakafi (ruxolitinib)
  • Jylamvo (methotrexate oral solution)
  • Lumoxiti (moxetumomab pasudotox-tdfk for injection)
  • Marqibo (vincristine sulfate liposome injection)
  • Rydapt (midostaurin capsules)
  • Rezlidhia (olutasidenib capsules)
  • Synribo (omacetaxine mepesuccinate)
  • Oncaspar (pegaspargase)
  • Vesanoid (tretinoin)
  • Valstar (valrubicin)