Drug details

Danyelza (naxitamab-gqgk injection)

type of Antineoplastics, Anti-GD2 Monoclonal Antibodies

Danyelza (naxitamab-gqgk) is a GD2-binding monoclonal antibody indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), to treat pediatric patients 1 year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who have demonstrated a partial response, minor response, or stable disease to prior therapy.

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • diarrhea,
  • headache,
  • fatigue,
  • cough,
  • anxiety,
  • irritability,
  • fast heart rate,
  • decreased lymphocytes,
  • decreased hemoglobin,
  • decreased neutrophils,
  • high blood pressure (hypertension),
  • decreased appetite,
  • fluid retention (edema),
  • decreased platelet count,
  • increased alanine aminotransferase,
  • erythema multiforme,
  • numbness and tingling of extremities,
  • hives not occurring on the day of infusion or the day following an infusion,
  • fever not occurring on the day of infusion or the day following an infusion,
  • injection site reaction,
  • localized swelling,
  • decreased potassium,
  • decreased glucose,
  • decreased calcium,
  • decreased albumin,
  • decreased sodium, and
  • decreased phosphate
The following drugs are related to Danyelza, either as a replacement or used together:
  • Adriamycin PFS (doxorubicin hydrochloride)
  • Cytoxan (cyclophosphamide)
  • Unituxin (dinutuximab injection)
  • Lunsumio (mosunetuzumab-axgb injection)
  • Thiotepa (thiotepa injection)
  • Vincristine Sulfate Injection (vincristine sulfate)