Drug details

Contrave (naltrexone hcl and bupropion hcl extended-release tablets)

type of Opioid Antagonists

Contrave (naltrexone HCl and bupropion HCl) Extended-release is a combination of an opioid antagonist and an antidepressant used as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of: 30 kg/m2 greater (obese) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

This drug may have the following side effects:
  • nausea,
  • headache,
  • dizziness,
  • vomiting,
  • diarrhea,
  • constipation,
  • tremor,
  • dry mouth,
  • trouble sleeping (insomnia),
  • rash,
  • anxiety,
  • increased sweating,
  • flu symptoms,
  • ringing in the ears,
  • fainting.
  • abdominal pain,
  • changes in taste,
  • urinary tract infection,
  • hot flashes,
  • palpitations,
  • fatigue,
  • high blood pressure,
  • muscle strain,
  • problems with attention,
  • lightheadedness, or
The following drugs are related to Contrave, either as a replacement or used together:
  • Belviq (lorcaserin hydrochloride)
  • Belviq XR (lorcaserin hydrochloride extended release tablets)
  • Imcivree (setmelanotide injection, for subcutaneous use)
  • Saxenda (liraglutide [rdna origin]) injection)
  • Xenical (orlistat 120 mg)
  • Qsymia (phentermine and topiramate)
  • Plenity (superabsorbent hydrogel particles in capsules)
  • Wegovy (semaglutide injection)