Drug details
CombiPatch (estradiol, norethindrone acetate transdermal system)
type of Estrogens/Progestins-HRT
CombiPatch (estradiol, norethindrone acetate transdermal system) is a combination of female hormones used to treat the symptoms of menopause such as feelings of warmth in the face, neck and chest, or sudden intense spells of heat and sweating ("hot flashes" or "hot flushes"); to treat vulvar and vaginal changes (itching, burning, dryness in or around the vagina, difficulty or burning with urination) caused by menopause; and to replace estrogen in conditions such as hypogonadism, removal of the ovaries, or primary ovarian failure that result in a lack of estrogen.
This drug may have the following side effects:
- nausea,
- vomiting,
- weakness,
- headache, or
- abdominal pain,
- bloating,
- weight changes.
- breast tenderness or enlargement,
- swelling of the hands or feet,
- spotty darkening of the skin (particularly on the face),
- vaginal irritation or discomfort,
- changes in menstrual cycle,
- skin redness/irritation/rash at the application site,
- difficulty wearing contact lenses,
- painful menstruation,
- breakthrough bleeding,
The following drugs are related to CombiPatch, either as a replacement or used together:
- Bavencio (avelumab injection)
- Lopreeza (estradiol/norethindrone acetate tablets)
- Fyavolv (norethindrone acetate and ethinyl estradiol tablets)