Drug details

Propulsid (cisapride (removed from us market))

type of Prokinetic Agents

Propulsid (cisapride) is a "prokinetic" agent that increases muscle contractions of the lower esophagus and the lower esophagus sphincter used to treat gastric reflux (the regurgitation of stomach acid into the esophagus), which is usually experienced as heartburn. The brand name Propulsid is no longer available in the U.S. Generic versions may be available.

This drug may have the following side effects:
  • chest pain,
  • nausea,
  • headache,
  • dizziness,
  • vomiting,
  • indigestion,
  • diarrhea,
  • cough,
  • sore throat,
  • runny or stuffy nose,
  • itching,
  • constipation,
  • joint pain,
  • nervousness,
  • fever,
  • depression,
  • insomnia,
  • rash,
  • vision problems, 
  • anxiety,
  • back pain,
  • gas,
  • fatigue,
  • abdominal pain,
  • pain,
  • urinary tract infection,
  • upper respiratory tract infection,
  • increased frequency of urination,
  • muscle pain.
  • vaginal infection, 
  • viral infection,
  • dehydration, and
The following drugs are related to Propulsid, either as a replacement or used together:
  • Reglan (metoclopramide)
  • Metozolv ODT (metoclopramide hydrochloride orally disintegrating tablets)
  • Zegerid (omeprazole, sodium bicarbonate)
  • Protonix (pantoprazole)
The following supplements are related to Propulsid, and may be used together with the drug:
  • Magnesium (s.)