Drug details

Sinemet CR (carbidopa-levodopa sustained release)

type of Decarboxylase Inhibitors

Sinemet CR (carbidopa-levodopa) Sustained-Release Tablets is a dopamine and antiparkinsonism drug used to treat Parkinson's disease. Sinemet CR is available in generic form.

This drug may have the following side effects:
  • nausea,
  • headache,
  • dizziness,
  • blurred vision,
  • vomiting,
  • diarrhea,
  • sleep problems (insomnia),
  • cough,
  • constipation,
  • loss of appetite,
  • dry mouth,
  • drowsiness,
  • sneezing,
  • muscle pain,
  • stuffy nose,
  • heartburn,
  • numbness or tingly feeling, or
  • strange dreams,
  • other cold symptoms,
  • skin rash or itching.
The following drugs are related to Sinemet CR, either as a replacement or used together:
  • Symmetrel (amantadine hydrochloride)
  • Kynmobi (apomorphine hydrochloride sublingual film)
  • Aricept (donepezil)
  • Azilect (rasagiline)
  • Cogentin (benztropine mesylate injection)
  • Parlodel (bromocriptine mesylate)
  • Rytary (carbidopa and levodopa capsules)
  • Duopa (carbidopa and levodopa enteral suspension)
  • Dhivy (carbidopa and levodopa tablets)
  • Stalevo (carbidopa, levodopa and entacapone)
  • Codeine Sulfate (codeine)
  • Eldepryl (selegiline hcl)
  • Fluorodopa FDOPA (f18 injection)
  • Levsin (hyoscyamine)
  • Inbrija (levodopa inhalation powder)
  • Nourianz (istradefylline tablets)
  • Kemadrin (procyclidine hydrochloride tablets)
  • Vyzulta (latanoprostene bunod ophthalmic solution)
  • Mirapex (pramipexole)
  • Mirapex ER (pramipexole dihydrochloride extended-release tablets)
  • Nuplazid (pimavanserin tablets)
  • Ongentys (opicapone capsules)
  • Requip XL (ropinirole extended release tablets)
  • Xadago (safinamide tablets)
  • Tasmar (tolcapone)
The following supplements are related to Sinemet CR, and may be used together with the drug:
  • Black Tea (s.)
  • Coenzyme Q-10 (s.)
  • Green Tea (s.)
  • Caffeine (s.)
  • Vitamin E (s.)
  • Coffee (s.)
  • Creatine (s.)