Drug details

Sinemet (carbidopa-levodopa)

type of Decarboxylase Inhibitors

Sinemet (carbidopa-levodopa) is a combination of an inhibitor of aromatic amino acid decarboxylation and an aromatic amino acid used to treat Parkinson symptoms such as

This drug may have the following side effects:

• diarrhea,
• confusion,
• sweating,
• very stiff (rigid) muscles,
• high fever,
• fast or uneven heartbeats,
• tremors, and
• lightheadedness
• depression,
• hallucinations,
• unusual changes in mood or behavior,
• severe or ongoing vomiting,
• suicidal thoughts,
• worsening of tremors (uncontrolled shaking),

The following drugs are related to Sinemet, either as a replacement or used together:

• Symmetrel (amantadine hydrochloride)
• Apokyn (apomorphine)
• Kynmobi (apomorphine hydrochloride sublingual film)
• Aricept (donepezil)
• Azilect (rasagiline)
• Cogentin (benztropine mesylate injection)
• Parlodel (bromocriptine mesylate)
• Rytary (carbidopa and levodopa capsules)
• Duopa (carbidopa and levodopa enteral suspension)
• Dhivy (carbidopa and levodopa tablets)
• Stalevo (carbidopa, levodopa and entacapone)
• Comtan (entacapone)
• Eldepryl (selegiline hcl)
• Fluorodopa FDOPA (f18 injection)
• Levsin (hyoscyamine)
• Inbrija (levodopa inhalation powder)
• Xeomin (incobotulinumtoxin a for injection)
• Nourianz (istradefylline tablets)
• Kemadrin (procyclidine hydrochloride tablets)
• Vyzulta (latanoprostene bunod ophthalmic solution)
• Mirapex (pramipexole)
• Mirapex ER (pramipexole dihydrochloride extended-release tablets)
• Nuplazid (pimavanserin tablets)
• Ongentys (opicapone capsules)
• Requip (ropinirole hcl)
• Requip XL (ropinirole extended release tablets)
• Xadago (safinamide tablets)
• Tasmar (tolcapone)

The following supplements are related to Sinemet, and may be used together with the drug:

• Black Tea (s.)
• Coenzyme Q-10 (s.)
• Green Tea (s.)
• Caffeine (s.)
• Vitamin E (s.)
• Coffee (s.)
• Creatine (s.)