Drug details

Probuphine (buprenorphine implant)

type of Analgesics, Opioid Partial Agonist

Probuphine (buprenorphine) implant for subdermal administration is a partial opioid agonist indicated for the maintenance treatment of opioid dependence in patients who have achieved and sustained prolonged clinical stability on low-to-moderate doses of a transmucosal buprenorphine-containing product (i.e., doses of no more than 8 mg per day of Subutex or Suboxone sublingual tablet or generic equivalent). Probuphine should be used as part of a complete treatment program to include counseling and psychosocial support.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • vomiting,
  • diarrhea,
  • fever,
  • lightheadedness,
  • confusion,
  • dizziness,
  • blurred vision,
  • nausea
  • sweating,
  • weakness,
  • agitation,
  • shivering,
  • runny nose,
  • slurred speech,
  • hallucinations,
  • twitching,
  • fast heart rate,
  • weak or shallow breathing,
  • extreme drowsiness,
  • muscle stiffness,
  • loss of coordination, and
  • breathing that stops during sleep,
  • worsening tiredness,
  • goose bumps,
  • increased sweating,
  • feeling hot or cold,
  • watery eyes,
  • changes in mental status,
  • trouble concentration,
  • problems with walking, reflexes or coordination,
The following drugs are related to Probuphine, either as a replacement or used together:
  • Bunavail (buprenorphine and naloxone buccal film)
  • Subutex (buprenorphine)
  • Cassipa (buprenorphine and naloxone sublingual film)
  • Zubsolv (buprenorphine and naloxone sublingual tablets)
  • Suboxone (buprenorphine hcl and naloxone hcl)
  • Dolophine (methadone tablets)
  • Methadose Oral Concentrate (methadone hydrochloride)
  • Methadone Hydrochloride Injection (methadone hydrochloride injection)
  • Methadose (methadone hydrochloride tablets)
  • Revia (naltrexone)
  • Vivitrol (naltrexone xr inj)