Drug details

Zulresso (brexanolone injection, for intravenous use)

type of Antidepressants, Other

Zulresso (brexanolone) Injection is a type of antidepressant called a neuroactive steroid gamma-aminobutyric acid (GABA) A receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adults. Zulresso is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the Zulresso REMS.

This drug may have the following side effects:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• lightheadedness,
• excessive drowsiness,
• sudden changes in mood or behavior,
• new or worsening depression, and
• thoughts of hurting yourself

The following drugs are related to Zulresso, either as a replacement or used together:

• Auvelity (dextromethorphan hydrobromide, bupropion hydrochloride)
• Celexa (citalopram hydrobromide)
• Lexapro (escitalopram oxalate)
• Zoloft (sertraline hcl)