Drug details

Zirabev (bevacizumab-bvzr injection)

type of Antineoplastics, VEGF Inhibitor

Zirabev (bevacizumab-bvzr) is a vascular endothelial growth factor inhibitor indicated for the treatment of metastatic colorectal cancer, in combination with intravenous fluorouracil-based chemotherapy for first- or second-line treatment; and metastatic colorectal cancer, in combination with fluoropyrimidine¬irinotecan- or fluoropyrimidine-oxaliplatin-based chemotherapy for second-line treatment in patients who have progressed on a first-line bevacizumab product-containing regimen. Zirabev is biosimilar to Avastin (bevacizumab).

This drug may have the following side effects:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• fever,
• easy bruising,
• lightheadedness,
• shortness of breath,
• confusion,
• chills,
• chest pain,
• dizziness,
• vision problems,
• pain spreading to your jaw or shoulder,
• seizure,
• swelling,
• headache,
• wheezing,
• fainting,
• sweating,
• cough,
• chest pain or pressure,
• sore throat,
• mouth sores,
• severe stomach pain,
• rapid weight gain,
• sudden numbness or weakness (especially on one side of the body),
• bloody or tarry stools,
• vomit that looks like coffee grounds,
• skin sores,
• urine that looks foamy,
• puffy eyes,
• swelling in your ankles or feet,
• unusual bleeding (nose, mouth, vagina, rectum),
• urine leakage,
• missed menstrual periods,
• blurred vision, and
• pounding in your neck or ears
• any bleeding that will not stop,
• sudden severe headache,
• problems with your vision or balance,
• stomach pain or swelling,
• chest pain and trouble breathing,
• feeling like you are choking,
• cough up blood,
• extreme weakness or tiredness,
• gagging when you eat or drink,
• pain, swelling, warmth, or redness in on or both legs,
• sudden redness, warmth, swelling, or oozing from your skin,
• any skin wound or surgical incision that will not heal,

The following drugs are related to Zirabev, either as a replacement or used together:

• Afinitor (everolimus tablets)
• Afinitor Disperz (everolimus tablets)
• Alymsys (bevacizumab-maly injection)
• Arimidex (anastrozole)
• Aromasin (exemestane)
• Avastin (bevacizumab)
• Cosela (trilaciclib for injection)
• Exkivity (mobocertinib capsules)
• Fareston (toremifene)
• Femara (letrozole)
• Fotivda (tivozanib capsules)
• Lumakras (sotorasib tablets)
• Nolvadex (tamoxifen citrate)
• Retevmo (selpercatinib capsules)
• Soltamox (tamoxifen citrate)
• Tepmetko (tepotinib tablets)
• Tivdak (tisotumab vedotin-tftv for injection)