Drug details

Mvasi (bevacizumab-awwb solution for intravenous infusion)

type of Antineoplastics, VEGF Inhibitor

Mvasi (bevacizumab-awwb) Solution is a vascular endothelial growth factor-specific angiogenesis inhibitor indicated for the treatment of metastatic colorectal cancer, with intravenous 5-fluorouracil–based chemotherapy for first- or second-line treatment; for metastatic colorectal cancer, with fluoropyrimidine-irinotecan- or fluoropyrimidine-oxaliplatin-based chemotherapy for second-line treatment in patients who have progressed on a first-line bevacizumab product-containing regimen; for non-squamous non-small cell lung cancer, with carboplatin and paclitaxel for first line treatment of unresectable, locally advanced, recurrent or metastatic disease; for glioblastoma, as a single agent for adult patients with progressive disease following prior therapy; for metastatic renal cell carcinoma with interferon alfa; and for cervical cancer, in combination with paclitaxel and cisplatin or paclitaxel and topotecan in persistent, recurrent, or metastatic disease.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • fever,
  • easy bruising,
  • lightheadedness,
  • shortness of breath,
  • confusion,
  • chills,
  • chest pain,
  • dizziness,
  • vision problems,
  • pain spreading to your jaw or shoulder,
  • severe headache,
  • swelling,
  • headache,
  • wheezing,
  • fainting,
  • sweating,
  • cough,
  • chest pain or pressure,
  • sore throat,
  • mouth sores,
  • severe stomach pain,
  • rapid weight gain,
  • sudden numbness or weakness (especially on one side of the body),
  • problems with vision or balance,
  • extreme tiredness,
  • bloody or tarry stools,
  • coughing up blood,
  • vomit that looks like coffee grounds,
  • skin sores,
  • urine that looks foamy,
  • puffy eyes,
  • swelling in your ankles or feet,
  • unusual bleeding (nose, mouth, vagina, rectum),
  • extreme weakness,
  • urine leakage,
  • pain, swelling, warmth, or redness in one or both legs,
  • missed menstrual periods,
  • blurred vision, and
  • pounding in your neck or ears
  • any bleeding that will not stop,
  • sudden severe headache,
  • stomach pain or swelling,
  • seizure (blackout or convulsions),
  • chest pain and trouble breathing,
  • feeling like you are choking or gagging when you eat or drink,
The following drugs are related to Mvasi, either as a replacement or used together:
  • Krazati (adagrasib tablets)
  • Rybrevant (amivantamab-vmjw for injection)
  • Imuran (azathioprine)
  • Welireg (belzutifan tablets)
  • CellCept (mycophenolate mofetil)
  • Cosela (trilaciclib for injection)
  • Rozlytrek (entrectinib capsules)
  • Exkivity (mobocertinib capsules)
  • Fotivda (tivozanib capsules)
  • Lumakras (sotorasib tablets)
  • Tivdak (tisotumab vedotin-tftv for injection)