Drug details

Orladeyo (berotralstat capsules)

type of Kallikrein Inhibitors

Orladeyo (berotralstat) is a plasma kallikrein inhibitor indicated for prophylaxis to prevent attacks of hereditary angioedema (HAE) in adults and pediatric patients 12 years and older.

This drug may have the following side effects:

• vomiting,
• diarrhea,
• abdominal pain,
• back pain, and
• gastroesophageal reflux disease (GERD).

The following drugs are related to Orladeyo, either as a replacement or used together:

• Berinert ([c1 esterase inhibitor (human)] freeze-dried powder)
• Cinryze (c1 esterase inhibitor [human] freeze dried powder)
• Ruconest (c1 esterase inhibitor [recombinant] intravenous injection)
• Haegarda (c1 esterase inhibitor subcutaneous [human] injection)
• Kalbitor (ecallantide injection)
• Firazyr (icatibant injection for subcutaneous administration)
• Sajazir (icatibant injection, for subcutaneous use)
• Takhzyro (lanadelumab-flyo injection)