Drug details

Avodart (dutasteride)

type of 5-Alpha-Reductase Inhibitors

Avodart (dutasteride) is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5 alpha-reductase used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Avodart helps improve urinary flow and may also reduce the need for prostate surgery later. Avodart is sometimes given with another medication called tamsulosin (Flomax). Avodart prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. Avodart may be available in generic form.

This drug may have the following side effects:

• impotence (trouble getting or keeping an erection),
• testicle pain or swelling,
• increased breast size, or
• breast tenderness.

The following drugs are related to Avodart, either as a replacement or used together:

• Uroxatral (alfuzosin hcl)
• Cardura (doxazosin mesylate)
• Cardura XL (doxazosin mesylate extended release tablets)
• Detrol (tolterodine tartrate)
• Detrol LA (tolterodine tartrate)
• Ditropan (oxybutynin tablets)
• Ditropan XL (oxybutynin chloride extended release tablets)
• Jalyn (dutasteride and tamsulosin hydrochloride capsules)
• Proscar (finasteride)
• Flomax (tamsulosin hydrochloride)
• Illuccix (kit for the preparation of gallium ga 68 gozetotide injection)
• Rapaflo Capsules (silodosin capsules)
• Sanctura (trospium chloride tablets)
• VESIcare (solifenacin succinate)

The following supplements are related to Avodart, and may be used together with the drug:

• Coenzyme Q-10 (s.)
• Beta-Sitosterol (s.)
• African Wild Potato (s.)
• Pumpkin (s.)
• Pygeum (s.)
• Rye Grass (s.)
• Saw Palmetto (s.)