Drug details

Apretude (cabotegravir extended-release injectable suspension)

type of HIV, Integrase Inhibitors

Apretude (cabotegravir extended-release injectable suspension) is an HIV-1 integrase strand transfer inhibitor (INSTI) indicated in at-risk adults and adolescents weighing at least 35 kg for PrEP to reduce the risk of sexually acquired HIV-1 infection. Individuals must have a negative HIV-1 test prior to initiating APRETUDE (with or without an oral lead-in with oral cabotegravir) for HIV-1 PrEP.

The drug is often used to treat HIV .

This drug may have the following side effects:
  • clay-colored stools, and
  • yellowing of the skin or eyes (jaundice)
  • nausea,
  • vomiting,
  • muscle or joint pain,
  • loss of appetite,
  • anxiety,
  • fever,
  • restlessness,
  • hives, 
  • difficulty breathing, 
  • swelling of your face, lips, tongue, or throat, 
  • extreme tiredness, 
  • feeling unwell, 
  • blisters or sores in or around your mouth, 
  • red or puffy eyes, 
  • swelling in your face or mouth, 
  • unusual mood changes, 
  • sadness, 
  • hopelessness, 
  • stomach pain (upper right side), 
  • dark urine, 
The following drugs are related to Apretude, either as a replacement or used together:
  • Aptivus (tipranavir)
  • Reyataz (atazanavir sulfate)
  • Cabenuva (cabotegravir; rilpivirine extended-release injectable suspension)
  • Prezista (darunavir)
  • Dovato (dolutegravir and lamivudine tablets)
  • Pifeltro (doravirine tablets)
  • Tivicay (doutegravir 50mg tablets)
  • Edurant (rilpivirine tablets)
  • Sustiva (efavirenz)
  • Genvoya (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide tablets)
  • Emtriva (emtricitabine)
  • Epivir (lamivudine)
  • Epivir-HBV (lamivudine tablets and oral solution)
  • Intelence (etravirine tablets)
  • Lexiva (fosamprenavir calcium)
  • Rukobia (fostemsavir extended-release tablets)
  • Trogarzo (ibalizumab-uiyk injection)
  • Selzentry (maraviroc)
  • Viramune (nevirapine)
  • Viramune XR (nevirapine extended-release tablets, for oral use)
  • Norvir (ritonavir capsules, oral solution)
  • Norvir Soft Gelatin Capsules (ritonavir)
  • Retrovir (zidovudine)
  • Retrovir IV (zidovudine injection)
  • Viread (tenofovir disoproxil fumarate)