Drug details

Apokyn (apomorphine)

type of Antiparkinson Agents, Dopamine Agonists

Apokyn (apomorphine hydrochloride injection) is a dopamine agonist, which works by helping restore the balance of dopamine in the brain, used to treat "wearing-off" episodes (muscle stiffness, loss of muscle control) in people with advanced Parkinson's disease.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • vomiting,
  • fever,
  • lightheadedness,
  • shortness of breath,
  • confusion,
  • chest pain,
  • drowsiness,
  • hallucinations,
  • ongoing nausea,
  • twitching,
  • uncontrollable movements of your eyes, lips, tongue, face, arms, or legs,
  • worsening of Parkinson symptoms,
  • fast or slow heartbeats,
  • daytime sleepiness,
  • unusual thoughts or behavior,
  • new or worsening cough,
  • pain when you breathe,
  • shortness of breath while lying down,
  • unexplained pain in your stomach, back, or legs,
  • swelling in your lower legs,
  • penis erection that is painful or lasts 4 hours or longer,
  • increased sexual urges,
  • unusual urges to gamble, and
  • other intense urges
The following drugs are related to Apokyn, either as a replacement or used together:
  • Symmetrel (amantadine hydrochloride)
  • Kynmobi (apomorphine hydrochloride sublingual film)
  • Aricept (donepezil)
  • Azilect (rasagiline)
  • Cogentin (benztropine mesylate injection)
  • Stalevo (carbidopa, levodopa and entacapone)
  • Sinemet (carbidopa-levodopa)
  • Exelon (rivastigmine tartrate)
  • Exelon Patch (rivastigmine transdermal system)
  • Fluorodopa FDOPA (f18 injection)
  • Inbrija (levodopa inhalation powder)
  • Nourianz (istradefylline tablets)
  • Mirapex (pramipexole)
  • Ongentys (opicapone capsules)
  • Permax (pergolide mesylate)
  • Requip (ropinirole hcl)