Drug details

Letairis (ambrisentan tablets)

type of PAH, Endothelin Antagonists

Letairis (ambrisentan) is an endothelin receptor antagonist used to treat pulmonary arterial hypertension (PAH). Letairis blocks the effects of endothelin-1, helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise.

This drug may have the following side effects:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• nausea,
• loss of appetite,
• itching,
• dark urine,
• clay-colored stools, and
• yellowing of the skin or eyes (jaundice)
• vomiting,
• fever,
• pale skin,
• lightheadedness,
• shortness of breath,
• cold hands and feet,
• tiredness,
• chest pain,
• severe shortness of breath,
• swelling,
• wheezing,
• unusual tiredness,
• stomach pain (upper right side),
• rapid weight gain,
• cough with foamy mucus,

The following drugs are related to Letairis, either as a replacement or used together:

• Adcirca (tadalafil tablets)
• Alyq (tadalafil tablets)
• Tracleer (bosentan)
• Flolan (epoprostenol sodium)
• Ventavis (iloprost)
• Liqrev (sildenafil oral suspension)
• Remodulin (treprostinil sodium)
• Revatio (sildenafil citrate)
• Tyvaso DPI (treprostinil inhalation powder)
• Tyvaso (treprostinil inhalation solution)
• Uptravi (uptravi selexipag tablets)