Drug details

Afinitor Disperz (everolimus tablets)

type of Antineoplastics mTOr Kinase Inhibitors

Afinitor Disperz (everolimus tablets for oral suspension) is a kinase inhibitor indicated for the treatment of postmenopausal women with advanced hormone receptor-positive, HER2 negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole; adults with progressive neuroendocrine tumors of pancreatic origin (PNET) and adults with progressive, well-differentiated, non-functional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic; adults with advanced renal cell carcinoma (RCC) after failure of treatment with sunitinib or sorafenib; adults with renal angiomyolipoma and tuberous sclerosis complex (TSC), not requiring immediate surgery; adult and pediatric patients aged 1 year and older with TSC who have subependymal giant cell astrocytoma (SEGA) that requires therapeutic intervention but cannot be curatively resected; and for adjunctive treatment of adult and pediatric patients aged 2 years and older with TSC-associated partial-onset seizures.

This drug may have the following side effects:
  • shortness of breath,
  • nausea,
  • headache,
  • vomiting,
  • diarrhea,
  • weakness,
  • cough,
  • itching,
  • constipation,
  • joint pain,
  • fever,
  • weight loss,
  • dry mouth,
  • insomnia,
  • nosebleed,
  • rash,
  • back pain,
  • fatigue,
  • abdominal pain,
  • changes in taste,
  • swelling of extremities,
  • high blood sugar (hyperglycemia),
  • decreased appetite,
  • swelling and sores inside the mouth,
  • infections (such as respiratory tract infection),
  • pain in extremities,
  • pneumonitis,
  • hair loss, and
  • hot flushes
The following drugs are related to Afinitor Disperz, either as a replacement or used together:
  • Krazati (adagrasib tablets)
  • Rybrevant (amivantamab-vmjw for injection)
  • Azedra (iobenguane i 131 injection)
  • Welireg (belzutifan tablets)
  • Zirabev (bevacizumab-bvzr injection)
  • Libtayo (cemiplimab-rwlc injection)
  • Cosela (trilaciclib for injection)
  • Vizimpro (dacomitinib)
  • Elzonris (tagraxofusp-erzs injection)
  • Fotivda (tivozanib capsules)
  • Fyarro (sirolimus protein-bound particles for injectable suspension)
  • Herzuma (trastuzumab-pkrb for injection)
  • Jaypirca (pirtobrutinib tablets)
  • Vitrakvi (larotrectinib capsules)
  • Lumakras (sotorasib tablets)
  • Margenza (margetuximab-cmkb injection, for intravenous use)
  • Poteligeo (mogamulizumab-kpkc injection)
  • Udenyca (pegfilgrastim-cbqv injection)
  • Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf injection)
  • Tepmetko (tepotinib tablets)