Drug details

Differin Gel .3% (adapalene)

type of Acne Agents, Topical

Differin (adapalene) Gel 0.3% is a topical (applied to the skin) medication similar to vitamin A used to treat severe acne in people who are at least 12 years old. Differin Gel 0.3% is available in generic form.

This drug may have the following side effects:
  • a brief sensation of warmth or stinging immediately after applying the medication.
The following drugs are related to Differin Gel .3%, either as a replacement or used together:
  • Absorica (isotretinoin)
  • Absorica LD (isotretinoin capsules)
  • Epiduo Forte (adapalene and benzoyl peroxide gel 0.3%/2.5%)
  • Differin Lotion .1 (adapalene lotion .1%)
  • Aklief (trifarotene cream)
  • Aktipak (erythromycin 3%-benzoyl peroxide 5% topical gel)
  • Altreno (tretinoin lotion)
  • Amzeeq (minocycline topical foam)
  • Arazlo (tazarotene lotion)
  • Avita (tretinoin gel)
  • Avita Cream (tretinoin)
  • BenzaClin (clindamycin and benzoyl peroxide)
  • Benzagel (benzoyl peroxide gel)
  • Onexton (cindamycin phosphate and benzoyl peroxide gel, 1.2%/3.75)
  • Cleocin T (clindamycin topical)
  • Clindacin P (clindamycin topical solution)
  • Neuac (clindamycin phosphate and benzoyl peroxide gel)
  • Veltin (clindamycin phosphate and tretinoin gel)
  • Dupixent (dupilumab injection)
  • Epuris (isotretinoin capsules)
  • Staticin (erythromycin topical solution 1.5%)
  • Sotret (isotretinoin capsules)
  • Zenatane (isotretinoin capsules)
  • Soolantra (ivermectin cream, 1%)
  • Klaron (sodium sulfacetamide lotion)
  • Solodyn (minocycline hydrochloride)
  • Minolira (minocycline hydrochloride extended-release tablets)
  • Retin-A (tretinoin)
  • Seysara (sarecycline tablets)
  • Sumaxin Wash and Topical Solution (sodium sulfacetamide and sulfur)
  • Twyneo (tretinoin and benzoyl peroxide cream)
The following supplements are related to Differin Gel .3%, and may be used together with the drug:
  • Zinc (s.)
  • Bovine Cartilage (s.)
  • Saccharomyces Boulardii (s.)
  • Alpha Hydroxy Acids (s.)
  • Guggul (s.)
  • Tea Tree Oil (s.)