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Drug details

Actos (pioglitazone hydrochloride)

type of Antidiabetics, Thiazolidinediones

Actos (pioglitazone hydrochloride) is a thiazolidinedione and increases the body's sensitivity to insulin. Actos is used for type 2 diabetes, not type 1 diabetes or diabetic ketoacidosis. Generic Actos is not available in the U.S., but is available in other countries as pioglitazone.

This drug may have the following side effects:
  • swelling,
  • unusual tiredness,
  • painful or difficult urination,
  • rapid weight gain,
  • pink or red urine,
  • new or worsening urge to urinate,
  • vision changes, and
  • shortness of breath (especially when laying down),
  • sudden, unusual pain in your hand, arm or foot
The following drugs are related to Actos, either as a replacement or used together:
  • Precose (acarbose)
  • Actoplus MET, Actoplus MET XR (pioglitazone hcl and metformin hcl)
  • Amaryl Tablets (glimepiride)
  • Avandamet (rosiglitazone maleate and metformin hcl)
  • Avandia (rosiglitazone maleate)
  • Baqsimi (glucagon nasal powder)
  • Byetta (exenatide injection)
  • Carospir (spironolactone)
  • Duetact (pioglitazone hydrochloride and glimepiride tablets)
  • Trulicity (dulaglutide injection, for subcutaneous use)
  • Glyxambi (empagliflozin and linagliptin tablets)
  • Synjardy XR Extended-release Tablets (empagliflozin and metformin hydrochloride extended-release)
  • Jardiance (empagliflozin tablets)
  • Exubera (insulin human [rdna origin])
  • Glucotrol (glipizide)
  • Metaglip (glipizide and metformin)
  • GlucaGen (glucagon [rdna origin]) for injection)
  • Glucophage, Glucophage XR (metformin hcl)
  • Glucovance (glyburide and metformin)
  • Glynase PresTab (micronized glyburide tablets)
  • Humalog 75-25 (75-25 insulin lispro suspension and 25 insulin lispro injection)
  • Humulin R U-500 Kwikpen (insulin human injection for subcutaneous use)
  • Levemir (insulin detemir)
  • Toujeo (insulin glargine injection for subcutaneous use)
  • Toujeo U 300 (insulin glargine injection for subcutaneous use)
  • Janumet (sitagliptin metformin hcl)
  • Januvia (sitagliptin phosphate)
  • Victoza (liraglutide [rdna] injection)
  • Riomet (metformin hcl)
  • Metolazone (metolazone tablets)
  • Starlix Tablet (nateglinide)
  • Novolin R (recombinant dna origin)
  • NovoLog Mix 50/50 (50% insulin aspart protamine suspension and 50% insulin aspart injection)
  • Symlin (pramlintide acetate injection)
  • Prandin (repaglinide)
  • Rybelsus (semaglutide tablets)
The following supplements are related to Actos, and may be used together with the drug:
  • Magnesium (s.)
  • Acetyl-L-Carnitine (s.)
  • Beer (s.)
  • Wine (s.)
  • Iodine (s.)
  • Blond Psyllium (s.)
  • Caffeine (s.)
  • Capsicum (s.)
  • Gamma Linolenic Acid (s.)
  • Ginkgo (s.)
  • Coffee (s.)
  • Glucomannan (s.)
  • Guar Gum (s.)
  • Oats (s.)
  • Soy (s.)
  • Xanthan Gum (s.)
  • Agaricus Mushroom (s.)
  • Alpha-Lipoic Acid (s.)
  • Chromium (s.)
  • Ginseng, Panax (s.)
  • Milk Thistle (s.)
  • Prickly Pear Cactus (s.)
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