Drug details

Actoplus MET, Actoplus MET XR (pioglitazone hcl and metformin hcl)

type of Antidiabetics, Biguanides/Thiazolidinediones

Actoplus MET (pioglitazone hydrochloride and metformin hydrochloride) is a combination of 2 oral diabetes medicines for people with type 2 diabetes who do not use daily insulin injections. Actoplus MET is not for treating type 1 diabetes. Actoplus MET is available in generic form.

The drug is often used to treat Diabetes .

This drug may have the following side effects:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• nausea,
• loss of appetite,
• dark urine,
• vomiting,
• pale skin,
• lightheadedness,
• shortness of breath,
• tiredness,
• stomach pain,
• yellowing of the skin or eyes (jaundice),
• dizziness,
• swelling,
• weakness,
• unusual tiredness,
• painful or difficult urination,
• shortness of breath, and
• rapid weight gain,
• feeling cold,
• cold hands and feet
• changes in your vision,
• unusual muscle pain,
• pink or red urine,
• slow or irregular heart rate,
• new or worsening urge to urinate,

The following drugs are related to Actoplus MET, Actoplus MET XR, either as a replacement or used together:

• Actos (pioglitazone hydrochloride)
• Avandamet (rosiglitazone maleate and metformin hcl)
• Avandia (rosiglitazone maleate)
• Avapro (irbesartan)
• Cozaar (losartan potassium)
• Zegalogue (dasiglucagon injection)
• Duetact (pioglitazone hydrochloride and glimepiride tablets)
• Monopril (fosinopril sodium)
• Monopril HCT (fosinopril sodium-hydrochlorothiazide tablets)
• Glucotrol (glipizide)
• Glucotrol XL (glipizide extended release)
• Glucovance (glyburide and metformin)
• Humalog (insulin lispro (human analog))
• Lantus (insulin glargine [rdna origin] injection)
• Lyumjev (insulin lispro-aabc injection)
• Januvia (sitagliptin phosphate)

The following supplements are related to Actoplus MET, Actoplus MET XR, and may be used together with the drug:

• Magnesium (s.)
• Acetyl-L-Carnitine (s.)
• Beer (s.)
• Wine (s.)
• Iodine (s.)
• Blond Psyllium (s.)
• Caffeine (s.)
• Capsicum (s.)
• Gamma Linolenic Acid (s.)
• Ginkgo (s.)
• Coffee (s.)
• Glucomannan (s.)
• Guar Gum (s.)
• Oats (s.)
• Soy (s.)
• Xanthan Gum (s.)
• Agaricus Mushroom (s.)
• Alpha-Lipoic Acid (s.)
• Chromium (s.)
• Ginseng, Panax (s.)
• Milk Thistle (s.)
• Prickly Pear Cactus (s.)