Drug details

Actonel with Calcium (risedronate sodium with calcium carbonate)

type of Bisphosphonate Derivatives, Calcium Metabolism Modifiers

Actonel with Calcium (risedronate sodium with calcium carbonate) is a combination of a bisphosphonate with the mineral calcium used to treat or prevent postmenopausal and steroid-induced osteoporosis. Risedronate is also used to treat Paget's disease of bone. Calcium carbonate is used to prevent and to treat calcium deficiencies. The brand name Actonel with Calcium is discontinued, but generic versions may be available.

The drug is often used to treat Osteoporosis .

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • fever,
  • chest pain,
  • numbness,
  • swelling,
  • sore throat,
  • skin pain,
  • coughing up blood,
  • severe heartburn,
  • burning in your eyes,
  • red or purple skin rash that spreads and causes blistering and peeling,
  • muscle spasms or contractions, and
  • numbness or tingly feeling (around your mouth, or in your fingers and toes)
  • new or worsening heartburn,
  • difficulty or pain when swallowing,
  • pain or burning under the ribs or in the back,
  • burning pain in your upper stomach,
  • new or unusual pain in your thigh or hip,
  • jaw pain,
  • severe joint, bone or muscle pain,
The following drugs are related to Actonel with Calcium, either as a replacement or used together:
  • Tymlos (abaloparatide injection)
  • Activella (estradiol, norethindrone acetate)
  • Actonel (risedronate sodium)
  • Fosamax (alendronate sodium)
  • Fosamax Plus D (alendronate sodium and cholecalciferol)
  • Binosto (alendronate sodium effervescent tablets)
  • Boniva (ibandronate sodium)
  • Boniva Injection (ibandronate sodium injection)
  • Fortical (calcitonin-salmon (rdna origin))
  • Prolia (denosumab injection)
  • Didronel (etidronate disodium)
  • Estraderm (estradiol transdermal)
  • Femtrace (estradiol acetate tablets)
  • Estring (estradiol vaginal ring)
  • Menest (estrogens)
  • Reclast (zoledronic acid injection)
The following supplements are related to Actonel with Calcium, and may be used together with the drug:
  • Zinc (s.)
  • Magnesium (s.)
  • Calcium (s.)
  • Fish Oil (s.)
  • Vitamin D (s.)
  • Copper (s.)
  • Beta-Carotene (s.)
  • Dhea (s.)
  • St. John's Wort (s.)
  • Propionyl-L-Carnitine (s.)
  • Kava (s.)
  • Soy (s.)
  • Strontium (s.)
  • Black Cohosh (s.)
  • Fluoride (s.)
  • Ipriflavone (s.)
  • Manganese (s.)