Drug details

Abecma (idecabtagene vicleucel suspension)

type of CAR-T Cell Therapies

Abecma (idecabtagene vicleucel) is a B-cell maturation antigen (BCMA)-directed genetically modified autologous T cell immunotherapy used to treat adult patients with relapsed or refractory multiple myeloma after four or more prior lines of therapy, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody.

The drug is often used to treat Multiple myeloma .

This drug may have the following side effects:
  • nausea,
  • diarrhea,
  • fever,
  • upper respiratory tract infection,
  • musculoskeletal pain,
  • headache,
  • fatigue,
  • cough,
  • anemia
  • cytokine release syndrome (CRS),
  • decreased appetite,
  • fluid retention (edema),
  • infections,
  • hypogammaglobulinemia,
  • viral infections,
  • encephalopathy,
  • low white blood cells (neutropenia, leukopenia, lymphopenia),
  • low platelets (thrombocytopenia), and
The following drugs are related to Abecma, either as a replacement or used together:
  • Aphexda (motixafortide for injection)
  • Aredia (pamidronate disodium)
  • Blenrep (belantamab mafodotin-blmf for injection)
  • BiCNU (carmustine)
  • Velcade (bortezomib)
  • Kyprolis (carfilzomib)
  • Carvykti (ciltacabtagene autoleucel for iv injection)
  • Darzalex Faspro (daratumumab and hyaluronidase-fihj injection)
  • Darzalex (daratumumab intravenous injection)
  • Empliciti (elotuzumab for injection)
  • Evomela (melphalan for injection, for intravenous use)
  • Farydak (panobinostat capsules)
  • Sarclisa (isatuximab-irfc injection)
  • Ninlaro (ixazomib capsules)
  • Jaypirca (pirtobrutinib tablets)
  • Revlimid (lenalidomide)
  • Mozobil (plerixafor injection)
  • Pomalyst (pomalidomide capsules)
  • Xpovio (selinexor tablets)
  • Tecvayli (teclistamab-cqyv injection)
  • Zometa (zoledronic acid for inj)